À Los Angeles, Howard Payne, terroriste psychopathe, prend en otage un ascenseur dans un immeuble d'affaires en échange d'une rançon. Deux inspecteurs, Jack Traven et Harry Temple, parviennent à déjouer les plans du terroriste et à libérer les otages. Quelque temps plus tard, Payne est bien décidé à prendre sa revanche. Il récidive en posant une bombe sous un bus qui explosera si celui-ci roule à moins de 80 km/h.
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